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Pharmaceutical chemistry increasingly depends on fluorinated functional groups to enhance metabolic stability, bioavailability, lipophilicity, and receptor binding precision. However, the controlled introduction of trifluoromethyl (CF₃)

Pharmaceutical chemistry increasingly depends on fluorinated functional groups to enhance metabolic stability, bioavailability, lipophilicity, and receptor binding precision. However, the controlled introduction of trifluoromethyl (CF₃)